KMID : 0370219860300030121
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Yakhak Hoeji 1986 Volume.30 No. 3 p.121 ~ p.127
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Biopharmaceutical Studies on the Alkanol Esters of Naproxen(I) - Synthesis of 3 Kinds of the Alkanol Esters of Naproxen -
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¹é¿ìÇö/Paik WH
±èÁ¾°©/Kim JK
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Abstract
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Three new alkanol esters of d-2-(6-methoxy-2-naphthyl)propionic acid, NAPROXEN were synthesized by esterification of sodium naproxen with chloralcohols, such as 2-chloroethanol, 3-chloro-1, 2-propanediol and beta-chloroethoxyethanol in dimethylformamide. These new esters were obtained with comparably high yield and identified by elemental analysis, UV, IR and NMR techniques.
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KEYWORD
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